Secukinumab Associated with Acitretin in Generalized Pustular Psoriasis

Successful use of secukinumab in pustular psoriasis

BSA: body surface area DLQI: Dermatology Life Quality Index IL-17A: interleukin-17A PASI: Psoriasis Area and Severity Index INTRODUCTION Psoriasis is a common chronic immunologic condition of the skin and nails that affects approximately 2% of the population and is characterized by red elevated plaques with silvery scale. Various forms exist, of which, chronic plaque psoriasis is most common, o...

Secukinumab in the Treatment of Generalized Pustular Psoriasis: A Case report.

Infantile acute erythrodermic pustular psoriasis with a good response to acitretin monotherapy

Infliximab in recalcitrant generalized pustular arthropatic psoriasis.

Generalized pustular psoriasis is an unstable inflammatory type of psoriasis, with widespread areas of erythema and sterile pustules, associated with fever and systemic symptoms. Infliximab is a monoclonal antibody with anti-TNFalpha activity, approved for use in psoriasis. We describe a male patient with a long history of stable arthropathic psoriasis, hospitalized with a generalized pustular ...

Homozygous missense mutation in IL36RN in generalized pustular dermatosis with intraoral involvement compatible with both AGEP and generalized pustular psoriasis.

Acquisition, analysis, or interpretation of data: All authors. Drafting of the manuscript: Sanlorenzo, Vujic, Cleaver, Ortiz-Urda. Critical revision of the manuscript for important intellectual content: Sanlorenzo, Vujic, Posch, Quaglino, Ortiz-Urda. Statistical analysis: Sanlorenzo. Obtained funding: Ortiz-Urda. Administrative, technical, or material support: Vujic, Cleaver, Ortiz-Urda. Study ...